Cun Yu Wang Ph.d Dds

wangc

Professor and Chair
Divison of Oral Biology and Medicine
Dr. No-Hee Park Endowed Chair in Dentistry

310-825-4415

Education

  • BDS, Nanjing Medical University, 1985
  • DDS, Perking University School of Dentistry, 1989
  • Postdoctoral Fellow, Forsyth Institute/Harvard University, 1995
  • Ph.D, University of North Carolina at Chapel Hill, Genetics and Molecualr Biology, 1998

    Research Grants and Honors

    Research Grants

    • NIH/NIDCR R01 (DE15964) (PI), 2004 – 2009
    • Molecular and Genetic Determinants of Invasions in HNSCC
    • NIH/NIDCR R01 DE1016513 (PI), 2005 – 2010
    • Molecular Regulation of Dental Stem Cell Property
    • GSK Oral Innovation Care Award GlaxoSmithKline, 2007 – 2009
    • NIH/NIDCR R01 DE017684 (PI), 2008 – 2013
    • Inhibition of Bone Formation by TNF/NF kB signaling

    Honors

    • Member, Board of Scientific Counselors, NIH/NIDCR, 2007
    • William Gies Award for Biological Research, Journal of Dental Research, 2003
    • Young Investigator Award, IADR, 1999

     Recent Publications

    1. Krum S.A., Chang J., Miranda-Carboni G., Wang C.Y., “Novel functions for NFkB: inhibition of bone formation,” Nat Rev Rheumatol. 2010 Oct;6(10);607-11. Epub 2010 Aug 10.
    2. Rheman A.O., Wang C.Y., “CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex,” Int J Oral Sci. 2009 Sep;1(3):105-18.
    3. Sun S., Wang Q., Giang A., Cheng C., Soo C., Wang C.Y., Liau L.M., Chiu R., “Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB,” J Neurooncol. 2011 Jan;101(1):1-14. Epub 2010 May 9.
    4. Fan Z., Yamaza T., Lee J.S., Yu J., Wang S., Fan G., Shi S., Wang C.Y., “BCOR regulates mesenchymal stem cell function by epigenetic mechanisms,” Nat Cell Biol. 2009 Aug;11(8):1002-9. Epub 2009 Jul 5.
    5. Tang E.D., Wang C.Y., “MAVS self-association mediates antiviral innate immune signaling,” J Virol. 2009 Apr;83(8):3420-8. Epub 2009 Feb 4.
    6. Rehman A.O., Wang C.Y., “SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NF-kappaB,” J Biol Chem. 2008 Jul 18;283(29):19888-94. Epub 2008 Apr 30.
    7. Li J., Wang C.Y., “TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis,” Nat Cell Biol. 2008 Feb;10(2):160-9. Epub 2008 Jan 13.