Elliot Landaw Phd

landaw

Professor and Chair
Department of Biomathematics

310-825-6743

Education

  • MD, University of Chicago, 1972
  • PhD, University of California, Los Angeles, 1980

Research Interests

Dr. Elliot Landaw’s research interests center on kinetic
analysis, compartmental modeling, nonlinear estimation and optimization
problems in pharmacokinetics, physiology and molecular biology. His
methodological interests in parameter estimation, optimal/robust sampling
designs and adaptive control for computational models address problems arising
from a variety of collaborations with experimental and clinical groups. Applied
projects include the optimal design of DNA-sequence reading molecules, the use
of model-based adaptive control for cancer chemotherapy and modeling glucose
transport across the blood-brain barrier.

 

Recent Papers

  1. Patel M., Gonzalez R., Halford C., Lewinski M.A., Landaw E.M., Churchill B.M., Haake D.A., “Target-specific capture enhances sensitivity of electrochemical detection of bacterial pathogens,” J Clin Microbiol. 2011 Dec;49(12):4293-96.
  2. Hernandez-Davies J.E., Zape J.P., Landaw E.M., Tan X., Presnell A., Griffith D., Heinrich M.C., Glaser K.B., Sakamoto K.M., “The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway,” Mol Cancer Ther. 2011 Jun;10(6):949-59. Epub 2011 Apr 6.
  3. Mastali M,. Babbitt J.T., Li Y., Landaw E.M., Gau V., Churchill B.M., Haake D.A., “Optimal probe length and target location for electrochemical detection of selected uropathogens at ambient temperature,” J Clin Microbiol. 2008 Aug;46(8):2707-16. Epub 2008 Jun 18.
  4. Cheng J.C., Kinjo K., Judelson D.R., Chang J., Wu W.S., Schmid I., Shankar D.B., Kasahara N., Stripecke R., Bhatia R., Landaw E.M., Sakamoto K.M., “CREB is a critical regulator of normal hematopoiesis and leukemogenesis,” Blood. 2008 Feb 1;111(3):1182-92. Epub 2007 Nov 1.
  5. Riedl M.A., Landaw E.M., Saxon A., Diaz-Sanchez D., “Initial high-dose nasal allergen exposure prevents allergic sensitization to a neoantigen,” J Immunol. 2005 Jun 1;174(11):7440-5.
  6. Shankar D.B., Cheng J.C., Kinjo K., Federman N., Moore T.B., Gill A., Rao N.P., Landaw E.M., Sakamoto K.M., “The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia,” Cancer Cell. 2005 Apr;7(4):351-62.
  7. Crans-Vargas H.N., Landaw E.M., Bhatia S., Sandusky G., Moore T.B., Sakamoto K.M., “Expression of cyclic adenosine monophosphate response-element binding protein in acute leukemia” Blood. 2002 Apr 1;99(7):2617-19.
  8. Yu R.C., Hattis D., Landaw E.M., Froines J.R., “Toxicokinetic interaction of 2,5-hexanedione and methyl ethyl ketone,” Arcg Toxicol. 2002 Jan;75(11-12):643-52.