Samuel Murray, MD

Recent Papers

1. Lee K.B., Murray S.S., Taghavi C.E., Song K.J., Brochmann E.J., Johnson J.S., Keorochana G., Liao J.C., Wang J.C., "Bone morphogenetic protein-binding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation," Spine J. 2011 Jun;11(6):568-76.
2. Sintuu C., Simon R.J., Miyazaki M., Morishita Y., Hymanson H.J., Taghavi C., Brochmann E.J., Murray S.S., Wang J.C., "Full-length spp24, but not its 18.5-kDa proteolytic fragment, inhibits bone-healing in a rodent model of spine fusion," J Bone Joint Surg Am. 2011 Jun 1;93(11):1022-32.
3. Lee K.B., Murray S.S., Duarte M.E., Spitz J.F., Johnson J.S., Song K.J., Brochmann E.J., Taghavi C.E,. Keorochana G., Liao J.C., Wang J.C., "Effects of the bone morphogenetic protein binding protein spp24 (secreted phosphoprotein 24 kD) on the growth of human lung cancer cells," J Orthop Res. 2011 Nov;29(11):1712-8. Epub 2011 Apr 20.
4. Sun A., Murray S.S., Simon R.J,. Jawien J., Behnam K., Miller T.A., Brochmann E.J., "Alanine-scanning mutations of the BMP-binding domain of recombinant secretory bovine spp24 affect cytokine binding," Connect Tissue Res. 2010 Dec;51(6):445-51. Epub 2010 Jul 8.
5. Taghavi C.E., Lee K.B., He W., Keorochana G., Murray S.S., Brochmann E.J., Uludag H., Behnam K., Wang J.C,. "Bone morphogenetic protein binding peptide mechanism and enhancement of osteogenic protein-1 induced bone healing," Spine (Phila Pa 1976). 2010 Nov 1;35(23):2049-56.
6. Brochmann E.J., Simon R.J,. Jawien J., Behnam K., Sintuu C., Wang J.C., Murray S.S., "Carboxy terminus of secreted phosphoprotein-24 kDa (spp24) is essential for full inhibition of BMP-2 activity," J Orthop Res. 2010 Sep;28(9):1200-7.
7. Brochmann E.J., Behnam K., Murray S.S., "Bone morphogenetic protein-2 activity is regulated by secreted phosphoprotein-24 kd, an extracellular pseudoreceptor, the gene for which maps to a region of the human genome important for bone quality," Metabolism. 2009 May;58(5):64-50. Review.
8. Sintuu C., Murray S.S., Behnam K., Simon R., Jawien J., Silva J.D., Duarte M.E., Brochmann E.J., "Full-length bovine spp24 [spp24 (24-203)] inhibits BMP-2 induced bone formation," J Orthop Res. 2008 Jun;26(6):753-8.
9. Murray E.J., Murray S.S., Simon R., Behnam K., "Recombinant expression, isolation, and proteolysis of extracellular matrix-secreted phosphoprotein-24 kDa," Connect Tissue Res. 2007;48(6):292-9.
10. Murray S.S., Brochmann E.J., Harker J.O., King E., Lollis R.J., Khaliq S.A., "A statistical model to allow the phasing out of the animal testing of demineralised bone matrix products," Altern Lab Anim. 2007 Aug;35(4):405-9.