James Liao Ph.D


Chancellor’s Professor
Department of Chemical and Biomolecular Engineering
Department of Bioengineering

5531 Boelter Hall
310-825-1656 | 310-206-4107 (fax)



  • BS, National Taiwan University
  • PhD, University of Wisconsin-Madison


Awards and Positions

  • Member, National Academy of Sciences, 2015
  • Academician, Academia Sinica, Taiwan, 2014
  • National Academy of Science Award for the Industrial Application of Science, 2014
  • ENI Award, Renewable Energy Prize, 2013
  • Member, National Academy of Engineering, 2013
  • White House “Champion of Change” for Innovations in Renewable Energy, 2012
  • Ralph M. Parsons Foundation Chair, University of California, Los Angeles, 2011
  • Presidential Green Chemistry Challenge Award, 2010
  • James E., Bailey Award, Society for Biological Engineering, 2009
  • Alpha Chi Sigma Award, American Institute of Chemical Engineers, 2009
  • Marvin J. Johnson Award, Biochemical Technology Division, American Chemical Society, 2009
  • Charles Thom Award, Society for Industrial Microbiology, 2008
  • Chancellor’s Professorship, University of California, Los Angeles, 2008
  • Merck Award for Metabolic Engineering, 2006
  • FPBE Division Award fro American Institute of Chemical Engineers, 2006
  • W.N. Lacey Lectureship in Chemical Engineering, California Institute of Technology, 2006
  • Professor of the Year, 2005
  • Fellow, American Institute for Medical and Biological Engineering, 2002
  • American Institute of Chemical Engineers, Student Chapter, University of California, Los Angeles, 1997
  • Professor of the Year, 1997
  • Texas Engineering Experiment Station Fellow, 1996
  • Halliburton Professorship, Texas A&M University, 1995
  • Texas Engineering Experiment Station Select Young Faculty Award, 1993
  • National Science Foundation Young Investigator Award, 1992
  • Du Pont Faculty Development Award, 1992
  • Research Initiation Award, NSF, 1990

Research Interests

  • Next-generation biofuels
  • Transcriptional and metabolic networks analysis
  • Gene-metabolic circuits
  • Nitric oxide metabolism
  • Fatty acid metabolism

Recent Papers

  1. Sriram G., Parr L.S., Rahib L., Liao J.C., Dipple K.M., “Moonlighting function of glycerol kinase causes systems-level changes in rat hepatoma cells,” Metab Eng. 2010 Jul;12(4):332-40. Epub 2010 Apr 20.
  2. Brynildsen M.P., Liao J.C., “An integrated network approach identifies the isobutanol response network of Escherichia coli,” Mol Syst Biol. 2009;5;277. Epub 2009 Jun 16.
  3. Boscolo R., Liao J.C., Roychowdhury V.P., “An information theoretic exploratory method for learning patterns of conditional gene coexpression from microarray data,” IEEE/ACM Trans Comput BIol Bionform. 2008 Jan-Mar;5(1):15-24.
  4. Chou K.J., Dodd J., Liao J.C., “Interactions of nitrosylhemoglobin and carboxyhemoglobin with erythrocyte,” Nitric Oxide. 2008 Mar;18(2):122-35. Epub 2007 Nov 7.
  5. Sriram G., Rahib L., He J.S., Campos A.E., Parr L.S. Liao J.C., Dipple K.M., “Global metabolic effects of glycerol kinase overexpression in rat hepatoma cells,” Mol Genet Metab. 2008 Feb;93(20:145-59. Epub 2007 Oct 29.
  6. Brynildsen M.P., Wu T.Y., Jang S.S., Liao J.C., “Biological network mapping and source signal deduction,” Bioinformatics. 2007 Jul 15;23(14):1783-91. Epub 2007 May 11.
  7. Bernstein J.R., Bulter T., Shen C.R., Liao J.C., “Directed evolution of ribosomal protein S1 for enhanced translational efficiency of high GC Rhodopseudomonas palustris DNA in Escherichia coli,” J Biol Chem. 2007 Jun 29;282(26):18929-36. Epub 2007 Apr 5.
  8. Rahib L., MacLennan N.K., Horvath S., Liao J.C., Dipple K.M., “Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling,” Eur J Hum Genet. 2007 Jun;15(6):646-57. Epub 2007 Apr 4.
  9. Brynildsen M.P., Tran L.M., Liao J.C., “A Gibbs sampler for the identification of gene expression and network connectivity consistency,” Bioinformatics. 2006 Dec 15;22(24):3040-6. Epub 2006 Oct 23.
  10. MacLennan N.K., Rahib L., Shin C., Fang Z., Horvath S., Dean J., Liao J.C., McCabe E.R., Dipple K.M., “Targeted disruption of glycerol kinase gene in mice: expression analysis in liver shows alterations in network partners related to glycerol kinase activity,” Hum Mol Genet. 2006 Feb 1;15(3):405-15. Epub 2005 Dec 20.