BioMEMS and Biomedical Nanotechnology: From Lab on Chip to Printing Cellular Machines

Integration of biology, medicine, and fabrication methods at the micro and nano scale offers tremendous opportunities for solving important problems in biology and medicine and to enable a wide range of applications in diagnostics, therapeutics, and tissue engineering. Microfluidics and Lab-on-Chip can be very beneficial to realize practical applications in detection of disease markers, counting of specific cells from whole blood, and for identification of pathogens, at point-of-care. In this talk, we will present data driven approaches for stratification of sepsis, detection of cells and proteins from a drop of blood, rapid detection of pathogens from body fluids, and spatial mapping of nucleic acids from cancer tumors. We will also present our work on bio-printing with stereolithography to produce bio-hybrid devices made of polymers and cells for the development of biological machines, soft robotics, and hyper organs. Such complex cellular systems will be a major challenge for the next decade and beyond, requiring knowledge from tissue engineering, synthetic biology, micro-fabrication and nanotechnology, systems biology, and developmental biology. These devices could have potential applications in drug delivery, power generation, and other biomimetic systems.

Seminar Flyer_Rashid Bashir